Medullary cords contain. The body of the lymph node is divided into an outer cortex and an inner medulla. B cells and plasma cells are the main cell types found in the medullary cords. In reactive lymph nodes, myeloid cells, mast cells, and plasma cells can be seen in the medullary cords. b: They are drained by efferent lymphatic vessels. It consists of three main parts: the midbrain, pons, and medulla oblongata. Aug 24, 2021 · The artery for the medulla oblongata’s lateral fossula gives birth to arterioles that supply the vagus nerve roots. Here, an artery, vein, and an efferent lymphatic vessel enter and leave the node. The medullary cords are aggregations of lymphoid tissue. A: Medullary cords are branched extensions of dense lymphatic tissue so they stain darkly and contain B-lymphocytes B: Medullary sinuses contain lymph, lymphocytes, macrophages and granulocytes and they function to drain the lymph. The hilum is a slight indentation on one side of the node. Medulla of lymph node Pictures Jul 25, 2023 · The medulla is the innermost layer of the lymph node and contains large blood vessels, sinuses, and medullary cords. NKD. Reticular fibers create an elaborate fibrous meshwork, called medullary cords, that serve as a scaffold for immune cells which can be exposed to pathogens as lymph flows through the medullary sinus. C. In addition to B cells and T cells, the cords contain plasma cells, macrophages The medulla of the lymph node consists of medullary sinuses, through which lymph percolates, and medullary cords, composed of B lymphocytes, macrophages, reticular cells and plasma cells. The deep cortical, and medullary cords contain B-cells and plasma cells. The cords contain macrophages and antibody-secreting B-cells called plasma cells. These also contain valves and emerge from a specific region of the node, the hilus. These are a type of white blood cell crucial for the immune response, particularly in producing antibodies that help combat infections and foreign substances. Nov 1, 2013 · Medulla: Portion of node closest to hilum Contains the medullary cords, sinuses and vessels but minimal number of follicles Medullary cords: Found in hilar region between the sinuses, composed mostly of small B and T lymphocytes, plasmacytoid lymphocytes, plasmablasts and plasma cells Sinuses: Carry lymph from afferent to efferent lymphatics Lymph node: medulla The medulla contains medullary cords and medullary sinuses located between the cords. It is located within the vertebral canal of the spine. They filter lymph. D. The medulla, characterized by lymphatic tissue arranged in branching and anastomosing medullary cords and medullary sinuses. It contains ascending sensory tracts that convey information about touch, vibration, and proprioception, and descending motor tracts that transmit motor commands from the brain to the spinal cord. No exceptions; all are true of lymph nodes. The outer cortex contains lymphoid follicles rich in B lymphocytes, while the inner medulla has medullary cords containing both B and T lymphocytes. From the hilum, the efferent lymphatic channels egress. To know the significance of the paracortical zone of the node. upper limbs, breasts, and superficial thorax. Medullary cords are rich in plasma cells, which are B cells that have differentiated to produce antibodies. —A mature germinal center has a basal population of large, closely packed centroblasts (CB) and an apical population of smaller, less closely packed centrocytes (CC). Medullary cords are strands of reticular fibers with lymphocytes and macrophages that extend from the cortex toward the hilus. The medulla of a lymph node is a central region characterized by its unique structural and functional components. The tunica albuginea, a fibrous connective tissue layer, forms around the cords. Study with Quizlet and memorize flashcards containing terms like The various macrophages are derived from what leukocytes, Which of the following are functional units of a lymph node: capsules, medullary cords, trabeculae, follicles, lymph sinuses, Which of the following cells help to regulate the immune response: NK cells, helper T cells, cytotoxic cells, B cells, plasma cells and more. Jan 16, 2021 · Medullary cords are the branching and anastomosing cords of typical lymphoid tissue; made with mainly T lymphocytes. Between the outer cortex and medulla lies an ill-defined region called the paracortex (inner cortex). The motor fibres that travel from the brain to the medulla oblongata and spinal cord are housed in the two pyramids. [5] The medullary cords are cords of lymphatic tissue, and include plasma cells, macrophages, and B cells. The lymph node also possesses structures called the medullary cords which are known to consist of antibodies, B-cells, and macrophages. 4). Jan 12, 2013 · Medullary cords These are lymphatic tissue cords and are comprised of B cells, macrophages, and plasma cells. Associated Disorders Node’s medulla contains medullary cords Connective tissue fibers that support B-lymphocytes, T-lymphocytes, and macrophages Additional functions of spleen: - Stores breakdown products of RBCs (e. Which is NOT correct regarding lymph The medullary sinus is the area in the lymph node where lymphatic fluid collects before it exits. , iron) for later reuse - Site of fetal erythrocyte production - In first 5 months of fetal life, spleen makes blood cells The National Center for Biotechnology Information provides comprehensive resources and research on various biological and medical topics. Dec 7, 2023 · The medullary cords of a lymph node primarily contain B cells and plasma cells, which are crucial to the adaptive immune system, with macrophages located in the medullary sinuses. 13-45 and 13-46). Within the medulla, the lymph circulates within the medullary sinuses or sinusoids. Reticular fibers are composed of thin and delicately woven strands of type III collagen. This contrast may be lessened if the sinuses contain large numbers of histiocytes and may be further obscured if the sinuses contain large numbers of lymphocytes (Figure 5). deep thoracic structures. Lymph nodes is one of the tissues that has a framework (or stroma) of reticular fibers. Sinuses are lined by sinus endothelial cells, whereas histiocytes and macrophages are most often seen within the sinuses. The cortex is distinct from the paracortex, which primarily contains T cells, and the medulla, which contains medullary cords and sinuses. The cells are arranged in cord-like projections extending centrally from the paracortex. The lymph node is an organ in the lymphatic system that filters interstitial fluid before it is eventually returned to the vascular system. Observe the sinuses at high magnification and observe that they are not clear channels, but instead contain many cells and fibers. abdominopelvic wall. Sep 27, 2023 · The medullary cords of a lymph node predominantly contain B cells. The structure Dec 5, 2024 · The medullary cavity is lined with endosteum, a thin layer of connective tissue, and contains bone marrow, blood vessels, and nerves, playing a crucial role in bone formation and hematopoiesis, surrounded by compact bone and spongy bone, facilitating skeletal growth and development. The medullary cords contain large numbers of plasma cells. head and neck. Functionality: Plasma cells produce large amounts of antibodies that are released into the lymph and subsequently into the bloodstream to help fight infections. These plasma cells secrete large quantities of antibodies into the lymph. The medulla also contains nuclei of multiple cranial nerves and serves as a conduit for ascending sensory and descending motor Which is NOT correct regarding lymph nodes? a: They contain strands of lymphatic cells supported by medullary cords. The interfollicular space contains many T cells and high endothelial venules. The cords also contain plasma cells, small lymphocytes and macrophages. Oct 27, 2025 · Human nervous system - Medulla, Brainstem, Reflexes: The medulla oblongata (myelencephalon), the most caudal segment of the brainstem, appears as a conical expansion of the spinal cord. The medullary cords are the primary location of plasma cells in the lymph node and contain a spectrum of cells from small B-lymphocytes to plasma cells with immunoblasts and plasmablasts. It is the transition from the spinal cord to the brain. The medullary sinuses are atypical lymphoid tissue located between the medullary cords of lymph node structure. A. Study with Quizlet and memorize flashcards containing terms like Lymphocytes provide an adaptive or specific defense known as the immune response. Nov 1, 2017 · Ovaries Primitive sex cords break into clusters of cells – form primary medullary cords Which is replaced by vascular stroma to form – medulla of ovary Coelomic epithelium proliferates again – forms 2nd generation of ovary (sex) cords Which will divide into clusters of cells – follicular cells of primary follicle It contains lymphatic nodules where B cells and macrophages proliferate. The medulla contains the vital autonomic cardiovascular and respiratory centers controlling heart rate, blood pressure, and breathing. They contain strands of lymphatic cells supported by medullary cords. Medulla Medulla is the lowest part of the brain stem and with other part of hindbrain occupies infratentorial space of the skull. upper limbs, breasts, and Part C Where in the lymph node do the T cells first encounter antigens presented by dendritic cells? medullary cords in the medulla lymphoid follicles of the outer cortex deep in the cortex germinal centers of the cortex deep in the cortex May 31, 2023 · The two most common structures seen in the medulla ot the lymph node are medullary cords and medullary sinuses (or sinusoids). BE. d: They filter lymph. The medullary cords of a lymph node contain lymphocytes and plasma cells. Apr 9, 2024 · Medulla: After passing through the cortex, the lymph progresses into the medulla of the lymph node. medullary NK cordal cytotoxic T B, The cell that dominates the deep cortical Aug 3, 2023 · Medulla The deepest layer of the lymph node is the medulla. Jul 24, 2021 · The medulla oblongata (or simply the medulla) is the most caudal part of the brainstem between the pons superiorly and spinal cord inferiorly. It is important to understand that lymphocytes include both B cells and T cells. Oct 31, 2019 · Medullary cords. The medulla is the deep, cavitated part of the lymph node; it is composed of medullary cords The cords are separated by spaces known as medullary sinuses The medullary sinuses converge at the hilum. The brainstem is a vital structure that connects the brain to the spinal cord and controls many essential life-sustaining functions. , The medullary cords of a lymph node contain ________ lymphocytes and plasma cells. In the cranial direction, the spinal cord is continuous with the medulla oblongata of the brainstem. The Medullary Spinal Cord Basics The Medullary Spinal Cord Basics The medullary spinal cord is a vital component of the central nervous system, serving as the main communication highway between the brain and the rest of the body. Filling the hilum is supporting connective tissue and adipose tissue. The medulla oblongata extends from the lower margin of the pons to a plane passing transversely below the pyramidal decussation and above the first pair The spinal cord is a long, thin, tubular structure made up of nervous tissue that extends from the medulla oblongata in the lower brainstem to the lumbar region of the vertebral column (backbone) of vertebrate animals. Medulla The medulla is the innermost part of the lymph node. It also helps control vital processes like your heartbeat, breathing and blood pressure. The spinal cord is a part of the central nervous system (CNS) along with the brain. . Examination of the photomicrograph reveals medullary cords within an open medullary sinus. inflammation of tissues. The medullary sinus is one of three sinuses in the lymph node, the others include the trabecular and subcapsular sinuses. Medullary sinuses Also known as sinusoids, these are vessel-shaped spaces that keep the medullary cords isolated. The roof plate of both the pons and the medulla is formed by the cerebellum and a membrane containing a cellular layer called the choroid plexus, located in the fourth ventricle. This region contains macrophages and antibody-secreting plasma cells. The medulla, where thymocytes migrate before leaving the thymus, contains a less dense collection of thymocytes, epithelial cells, and dendritic cells. In the medulla, locate the medullary cords and sinuses. Which is not correct regarding lymph nodes? A. The cells are arranged in medullary cords surrounded by medullary sinuses. They are drained by afferent lymphatic vessels. The medulla contains medullary cords (aggregates of lymphoid tissue) and medullary sinuses (lymphatic channels). phagocytic response. It contains medullary cords and medullary sinuses. The medullary sinuses drain the lymph coming from the cortical sinuses to the efferent lymphatic vessel via the hilum. The medulla contains plasma cells, macrophages, and B cells as well as sinuses, which are vessel-like spaces that the lymph flows into. Jul 28, 2014 · The areas between the medullary cords are the medullary sinuses. These contain reticular cells and histiocytes (macrophages that are incapable of movement). The light colored space (double arrows) between capsule (triangles) and dark cortex is the subcapsular sinus. The medullary cords are the major component of the lymph node medulla. The hilum contains a network of anastomosing efferent vessels that receive lymph passing through the medullary sinuses. An indented region, the hilum, which is surrounded by the medulla and contains connective tissue, a few fat cells, blood vessels, nerve bundles and large efferent lymphatic vessels with delicate valves to prevent the The white pulp contains nodules of lymphocytes (many with prominent germinal centers) and diffuse lymphatic tissue surrounding an artery (central artery with a periarterial lymphatic sheath - PALS). The answer is D. Medullary cords are supported by a network of interconnected FRCs and reticular fibers, whereby the latter are not entirely enveloped by the cytoplasmic extensions of FRCs, but remain uncovered toward the medullary cord tissue. This area is particularly rich in plasma cells that secrete antibodies into the lymphatic circulation, contributing to humoral immunity downstream of the node. There are fewer cells in the medulla. Plasma cells live for 3 days, and make IgG type antibodies. cytotoxic TC. cordal By signing The medulla of the lymph node is composed of medullary cords surrounded by medullary sinuses. The inner cortex contains mostly T-cells. Medullary cords contain both T and B cells and most of the plasma cells in the LN. The medullary sinuses are irregular spaces found between the medullary cords in the medulla of the lymph node. The medulla of a LN is a loose network of medullary cords and sinuses situated in the hilar area and separated loosely from the paracortex by a network of connective tissue fibers. Medulla The medulla forms the innermost region of the lymph node, containing medullary cords and sinuses that channel lymph toward efferent lymphatic vessels. The brainstem acts as a conduit for motor and sensory pathways between the brain and body and contains nuclei that control basic autonomic processes such as heart rate, breathing, and The medulla also serves as a relay station for sensory and motor information between the spinal cord and higher brain centers. Cell Types in Medullary Cords: B Cells: These lymphocytes are involved in producing antibodies, which are essential for identifying and neutralizing pathogens. Attached to the reticular fibers are lymphocytes and numerous macrophages, which can activate the immune system upon exposure to a pathogen The medulla oblongata is the most caudal portion of the brainstem, continuous inferiorly with the spinal cord and superiorly with the pons. [4-6] Oct 11, 2023 · Medullary cords are composed of B cells, plasma cells, macrophages, and other immune cells. Medulla. To describe the microanatomy of the spleen, including red and white pulp, blood vessels of red and white pulp, splenic sinusoids and cells. It contains two motor fibers (responsible for motor functions of the body): the corticospinal and corticobulbar tracts. None of the The medullary cords of a lymph node contain B lymphocytes and plasma cells which are key elements in the body's immune response. B e. A) cordal B) NK C) B D) medullary E) cytotoxic T Medulla of the Lymph Node: The medulla is the innermost part of the lymph node. NK d. Medulla SimpleMedulla diagram from Major Brainstem Nuclei & Tracts OverviewBrainstem: Longitudinal ViewHere, we will expand upon our understanding of the anatomy of the medulla. This diagram of a lymph node shows the pathways that lymphocytes can take, in and out of the lymph node. A. The cells are on their way to the efferent lymph. Between the cortex and medulla lies an ill-defined region called the paracortex which is rich in T The region indicated by number 1 is a? A. The medulla is the center of the node. Overall, the spinal cord extends between the foramen magnum - a large Jul 17, 2024 · The Y chromosome contains the SRY gene, which stimulates the development of the primitive sex cords to form testis (medullary) cords. To describe the structure of a lymph node and to identify cortex, medulla, trabeculae, medullary cords and sinusoidal system. Its location means it’s where your brain and spinal cord connect, making it a key conduit for nerve signals to and from your body. cordal 9) The medullary cords of a lymph node contain ________ lymphocytes and plasma cells. The medulla consists of a series of medullary cords (B-dependent areas), that are finger-like projections of lymphoid tissue, and large channels, called medullary sinuses that receive lymph from the cortical sinuses. Note the ingrowth of trabeculae from the capsule into the node. Jan 12, 2015 · The medulla consists of the medullary cords, which contain lymphocytes, macrophages, and plasma cells. You will also find the prominent plasma cells and also macrophage in the medullary cords in medulla of lymph node. The hilum of the lymph node is the location where blood vessels enter and exit the node. Afferent lymphatics enter from the convex surface, penetrate the capsule and enter the subcapsular sinus. Label the superior/inferior orientational plane and draw the different brainstem levels, from superior to inferior: - Midbrain - Pons - MedullaDiagram The medullary cords of a lymph node contain: reticular cells, lymphocytes, macrophages and plasma cells. medullaryB. cytotoxic T b. The medullary cords, which are found nearby, contain these B cells and plasma cells, forming an important part of the body's immune defense mechanisms. They are not visible with hematoxylin & eosin (H&E) or azan, but are specifically stained by In the medulla, parts of the cortical cell mass extends as the medullary cords. Study with Quizlet and memorize flashcards containing terms like Lymph Node, Cortex of Lymph Node, Medulla of Lymph Node and more. The medulla oblongata’s white matter contains all sensory (ascending) tracts and motor (descending) tracts that extend between the spinal cord and other parts of the brain. Aug 23, 2022 · The medullary pyramid consists of grouped white matter formations at the intersection between the brain and the spinal cord. Jun 14, 2017 · Medullary cords contain many B cells and plasma cells which are crucial for the production of antibodies. How does this arrangement suit the function of the lymph node? This arrangement of cells (mostly macrophages) and fibers (reticular) helps to filter lymph. The cords are populated by plasma cells, as well as B – cells and T – cells. Note the B-cell containing lymphoid follicles located in the cortex. In the medulla, the sinuses are lined by and filled with histiocytes, while the adjacent cords contain small lymphocytes and plasma cells. These cords branch and anastomose freely and are not prominent in a resting lymph node. Passageways through which lymph flows. Medullary cords are usually clearly delineated because their dense cellularity contrasts sharply against the sparse cellularity of the surrounding medullary sinuses. Study with Quizlet and memorize flashcards containing terms like The medullary cords in the image primarily contain which cell type? Macrophages Plasma Cells Neutrophils Lymphocytes, The star is located in which compartment of the lymph node? Medullary Sinus Cortex Sinus Medullary cord Cortex cord Nodule/Follicle, Which image of the lymph node represents one that is responding to a vaccine? A Each B-lymphocyte responds to one particular antigen. Study with Quizlet and memorize flashcards containing terms like lymph nodes, Large clusters of lymph nodes occur near, Lymph nodes have two basic protective functions: and more. A fine meshwork of reticular fibers and reticular cell processes crisscrosses this lymphatic sinus. Trabeculae, inward extensions of the capsule, partially divide the outer cortex into compartments and help direct lymph flow. In a stimulated node the cords become filled with antibody-secreting plasma cells. Cerebrospinal fluid entering medulla contains medullary cords (strands of connective tissue fibers that support B-lymphocytes, T-lymphocytes, and macrophages) ________ residing in the lymph node remove foreign debris from the lymph through phagocytosis macrophages lymphatic nodules structure and function The medulla is made up of reticular connective tissue. e: No exceptions; all are true of lymph nodes. Macrophages, plasma cells, fibroblasts, endothelial cells, T and B cells dominate the picture. medullary sinus. They are composed of reticular fibers, reticular cells, small lymphocytes, plasmocytes, and macrophages. In the medulla, the lymphoid tissue is organized as irregular cords of cells, medullary cords , surrounded by medullary sinuses . 17. It is one of the three main compartments of a lymph node, alongside the cortex and paracortex and is the innermost layer of the lymph node that contains large blood vessels, sinuses, and medullary cords, which are essential for the lymph node's role in filtering lymph and Medulla The medulla is composed of medullary cords and medullary sinuses between them. Mar 6, 2024 · Medulla: The medulla is the innermost region of the lymph node. In the caudal direction, it terminates as the medullary cone (conus medullaris). The medullary cords contain a large number of mature plasma cells, lymphocytes and macrophages. It contains medullary cords, which consist of plasma cells, B cells, macrophages, and antibody-producing cells. High endothelial venules (HEVs) are present in the cortex, allowing the entry of circulating lymphocytes into the lymph node. c: They contain macrophages. The lymph circulates through sinuses located in the cortex (containing the lymph nodules) and the medulla (containing lymphatic cords), and leaves the node via larger but fewer efferent lymphatic vessels. The medulla also contains medullary sinuses, which are interconnected spaces that drain lymphatic fluid towards the efferent lymphatic vessels. The center of the spinal cord is hollow and contains a structure called the central canal, which contains cerebrospinal fluid. Lymph node, showing medullary cords extending inwardly from capsule (triangle) and separated by lighter colored medullary sinuses (large arrows). It is the direct and expanded upward continuation of spinal cord and includes important fiber tracts (Fig. The red pulp contains sinusoids (large blood vessels), arteries (pulp artery), veins and cords of cells called the Cords of Billroth. They contain primarily T and B lymphocytes, plasma cells, and macrophages, contributing to immune responses within the lymph node. germinal center. It contains medullary cords, which are strands of lymphatic tissue that house immune cells. The medullary cords contain antibody-secreting plasma cells, B-cells, and macrophages. The hilum is the indented portion of lymph nodes where the efferent lymphatics and venules exit and where arterioles enter. Between the cortex and medulla lies an ill-defined region called the paracortex. medullary cord. 1. Aug 3, 2023 · Medulla The lymphocytes of the medulla are less organized and form irregular medullary cords. These are vessel-like spaces that separate the medullary cords, which contain antibody-secreting plasma cells, B-cells, and macrophages. Figure 18 2 1: Location, Structure, and Histology of the Thymus The thymus lies above the heart. lymphocytic response. a. The cortex contains a high concentration of lymphocytes while the inner medulla is less cellular. It is located within the vertebral column and extends from the base of the skull to the lower back, roughly spanning the length of the vertebral column. cortical sinus. [4-6] Medulla Oblongata Your medulla oblongata is the bottom-most part of your brain. The pyramidal tracts are made up of corticobulbar and corticospinal fibres. It houses essential autonomic centers that regulate cardiovascular, respiratory, and reflexive activities vital for survival. Less dense than the surrounding cortex, the medulla primarily contains T cells. 3. The medullary sinuses are contiguous with the efferent lymphatics, and contain lymph, macrophages, plasma cells, and mast cells. Medullary Sinuses - spaces surrounding medullary cords in which lymph from the cortex accumulates before exiting the node. [18] The medulla contains large blood vessels, sinuses and medullary cords that contain antibody-secreting plasma cells. The medulla is composed of medullary cords and medullary sinuses (see Figs. Answer to: The medullary cords of a lymph node contain lymphocytes and plasma cells. The medullary cords located near the hilum of the node contain mainly plasma cells and small lymphocytes. Subclavian trunks drain lymph from the? A. The medullary sinuses, on the other hand, provide a pathway for lymph and immune cells to exit the lymph node. The plasma cells are capable of secreting antibodies into the medullary sinuses or migrate into the sinus so that they enter the lymph that is transported into the efferent lymphatic vessel, and eventually enters the circulatory system. The medullary cords are composed primarily of B lymphocytes and plasma cells along with macrophages, lymphocytes and reticular cells. The sinuses contain reticular cells, reticular fibers, and scattered lymphocytes. It is subdivided functionally and histologically into two other regions; which are the medullary cords and sinuses. B. Note the outer cortex containing lymph nodules and its transition to the inner medulla . adaptive defense. Lymph flows past the cords through lymphatic channels called medullary sinuses. The reticular cells are fibroblast-like and electron micrographs show their processes completely enclosing (surrounding) the reticular fibers which they produce. Within the medulla, tongues of cortical tissue (medullary cords) that contain many activated B cells or their plasma cell descendants alternate with medullary sinuses. medullary c. Mid-sagittal section Start a mid-sagittal section, of the brainstem. Medullary cord is a portion of the medulla of the lymph node which contains lymphatic tissue and project into the medullary sinus. The medullary cords contain macrophages, lymphocytes, and plasma cells. Mar 26, 2025 · 5. Sep 16, 2023 · The medullary cords of a lymph node contain B lymphocytes and plasma cells, which are both crucial parts of our immune system, especially in producing antibodies. The small lymphocytes in the medullary cords, like elsewhere, have small rounded nuclei with fine chromatin and little cytoplasm. Inside each sinus cavity is a nodule, a smaller, denser bundle of lymphoid tissue that usually contains a germinal center, the site of B cell proliferation during antigen presentation. They contain phagocytic cells. The medulla is composed of medullary sinuses lined by lining cells and medullary cords containing various cell types. Space that contains medullary cords and macrophages in a lymph node. mantle zone. The medullary sinuses are lined by fibroblastic reticular cells and contain macrophages (“sinus histiocytes”), which cling to Medullary Cords - irregular cords that contain plasma cells, B lymphocytes, and macrophages. E. These structures all play a vital role in the adaptive immunity of a person. szh il8lu xbn abf gefb6s syx z6 rqf ea6t6 kxwvm